Barely Significant
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Cardiorenal Outcomes With Tirzepatide Compared With Dulaglutide in Patients With Diabetes and Cardiovascular Disease: A Post Hoc Analysis of the SURPASS-CVOT Randomized Clinical Trial.

JAMA Cardiol · 2026 · PMC13033170 · PMID 41903177

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marginally significantno p-value reported
There was a marginally significant interaction for BMI category (<27, 27-30, and >30), but no interaction for sex, age (<65 or ≥65 years), region of enrollment, race, ethnicity, hemoglobin A 1c level (≤8.5% or >8.5%), duration of diabetes (<10 years or ≥10 years), history of MI, history of congestive heart failure, impaired kidney function, or baseline SGLT-2 inhibitor use.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.