Altered lipid peroxidation, perineuronal net and oligodendrocyte markers in the frontal cortex of a dual-hit neurodevelopmental model support its relevance to schizophrenia.

The two studies where decreases failed to reach significance (∼17%) both used western blotting ( Mitkus et al., 2008 ; Hercher et al., 2014 ), and one acknowledged a potential confound arising from high CNPase expression in subgroups who disclosed moderate to heavy alcohol or other substance use ( Hercher et al., 2014 ).

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