Identification and dual-center histological validation of EMT core genes in chronic rhinosinusitis with nasal polyps: an integrated multi-cohort transcriptomic and single-cell analysis.

Front Immunol · 2026 · PMC13035518 · PMID 41924281

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a decreasing trendno p-value reported

an increasing trendno p-value reported

In histological validation using LN samples, E-cadherin showed a decreasing trend across HC, NECRSwNP, and ECRSwNP, whereas N-cadherin showed an increasing trend, supporting EMT activation.

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