Epigenetic profiling of hematopoietic stem cells from male mice identifies KDR and PU.1 as regulators of aging transcriptome and caloric restriction response.

Nat Commun · 2026 · PMC13035812 · PMID 41720793

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an overall trendno p-value reported

Genome-wide comparison of PU.1 binding demonstrated an overall trend of increased binding in OCR HSCs compared to OAL HSCs, which normalized after refeeding (Fig. 5d ).

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