highly significantP < 0.0005
A P -value < 0.05 (*) was considered statistically significant, P < 0.005 (**) was considered highly significant, and P < 0.0005 (***) was considered extremely significant.
A P -value < 0.05 (*) was considered statistically significant, P < 0.005 (**) was considered highly significant, and P < 0.0005 (***) was considered extremely significant.