Vitamin D supplementation in diabetic retinopathy: an optical coherence tomography angiography study of changes in macular perfusion.

A small trend toward improvement was seen in BCVA values, but its statistical significance was marginal (0.12 ± 0.13 to 0.10 ± 0.13 LogMAR, p = 0.051).

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Our main findings include: (i) FAZ metrics did not change significantly, (ii) parafoveal SVD at the superior quadrant was slightly reduced, but the rest of the perfusion density indices remained unchanged, (iii) changes in BCVA showed a slight trend toward improvement, but it was not associated with changes in vitamin D levels, and (iv) changes in none of the studied OCTA metrics were associated with increases in serum 25(OH)D3 level.

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