As patients with renal disease demonstrated a nonsignificant trend toward worsened survival with liberal fluid resuscitation in the parent CLOVERS study ( 2 ), an association of high chondroitin sulfate levels with early, subclinical renal failure could potentially explain the predictive capabilities of chondroitin sulfate observed in our study.
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Plasma chondroitin sulfate predicts the effectiveness of fluid resuscitation strategies in patients with sepsis.
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