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Integrated ICD-based subtyping and prognostic model reveal KCNN4 as a novel therapeutic target in NSCLC.

Discov Oncol · 2026 · PMC13038718 · PMID 41741906

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highly significantP = 0.0002actually significant
By day 3, the deficit was large and highly significant (sh-NC 2.21 ± 0.07 vs. sh-KCNN4 1.60 ± 0.13; mean difference 0.60 [95% CI 0.40–0.81]; adjusted P = 0.0002).These findings demonstrate a time-dependent and quantitatively large suppression of PC-9 proliferation following KCNN4 knockdown.

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