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A multi-epitope pan-betacoronavirus vaccine construct predicted to induce broad-spectrum and durable immune responses: an immunoinformatics approach.

Front Bioinform · 2026 · PMC13038886 · PMID 41929236

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an expected trendno p-value reported
The RMSD plot showed a rapid increase within the first 10 ns, stabilizing around 0.6 nm, which reflects rapid equilibration of the protein backbone in the solvent environment—an expected trend in well-equilibrated molecular systems ( Geisbrecht et al., 2002 ; Hollingsworth and Dror, 2018 ).

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