Impact of testosterone-based gender-affirming hormone therapy on toll-like receptor transcript levels and peripheral blood leukocyte counts in transmasculine individuals.

Front Immunol · 2026 · PMC13038929 · PMID 41929480

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a decreasing trendp = 0.048actually significant

MD2 showed a decrease in transcript level ( p = 0.031) ( Figure 2A ) and TLR2 displayed a decreasing trend ( Figure 2B ) ( p = 0.048); TLR1 and TLR3–7 showed no significant change (all p > 0.10) ( Supplementary Figure ).

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