highly significantp = 6×10 -4
In this context, among the associated modules, the dark grey module exhibited a moderate positive correlation with M-B- (r = 0.49, p = 0.05) and a strong, highly significant negative correlation with M+B+ (r = -0.76, p = 6×10 -4 ) ( Figure 5A ), reflecting a coherent and biologically meaningful inverse association with the transmission status.