Fructose and salt induce sex- and ovary dependent cardiac hypertrophy in Dahl salt-sensitive rats.

However, there was a borderline significant sex-diet interaction for βmhc expression ( p = 0.053), sustained by the substantial increase in DSS-OVX and the decrease in DSSM. 3.4 Gene expression regulating fibrosis and inflammation Table 4B and Figure 5 , show that high salt diet increase mRNA expression of collagen I ( col1 ) and III ( col 3 ) , tissue inhibitor of metalloproteinase1 ( timp1 ), tumor necrosis factor α ( tnf α ), monocyte chemoattractant protein-1 ( mcp-1 ) and transforming growth factor β2 (tgfβ2 ) .

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