Trisomy 21 Drives ADARB1 Overexpression and Premature RNA Recoding in the Developing Fetal Brain.

Nat Commun · 2026 · PMC13039865 · PMID 41917044

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AEI values were significantly elevated in T21 compared to controls in the PFC ( p = 0.01, linear regression), and showed a marginal trend in the hippocampus ( p = 0.05) (Fig. 5B ).

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