Transcriptome analysis of the prefrontal cortex identifies inflammatory genes associated with cognitive impairment in a model of multiple sclerosis.

Cell Death Discov · 2026 · PMC13039925 · PMID 41881968

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Coherently, Gene Set Enrichment Analysis (GSEA) revealed a highly significant enrichment in the “inflammatory response” hallmark and the “lymphocyte mediated immunity” and “response to chemokine” biological processes in the EAE PFC (Fig. 1D, E ).

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