On the other end, pyrimidine and purine metabolism show borderline significance in the analysis; however, their roles are crucial because purine and pyrimidine salvage pathways are well established in cancer, supplying the necessary building blocks for tumor cells to perform DNA and RNA synthesis [ 13 , 14 ].
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Serum Biomarkers in Bladder Cancer: NMR Metabolomics for Identification and Monitoring during Platinum-Based Therapy.
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