KEGG pathway enrichment analysis revealed that PI3K/Akt signaling, cytokine–cytokine receptor interaction, and calcium signaling pathways were highly significant, all known to promote stemness, drug resistance, and EMT (Figure 5b ) [ 67 , 68 , 69 , 70 , 71 , 72 , 73 ].
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Mechanical Stimuli-Induced Manipulation of Malignant Behavior in Bioprinted Cancer Microtissues via PI3K/NF-κB Activation.
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