Chronic methanol exposure induces cognitive impairment and Alzheimer's-like pathology in rhesus monkeys.

Figure 4L shows the expression of TDP‐43 protein in different groups of rhesus monkeys; compared to the control group, there is an increasing trend in TDP‐43 protein. 3.5 Mitochondrial and synaptic damage was detected in the brain tissue of rhesus monkeys exposed to methanol Using transmission electron microscopy to observe ultrastructural tissue allows for a more microscopic evaluation of tissue damage (Figure 5A ).

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