Plakoglobin transmits tension across VE-cadherin for vascular leak formation and leukocyte diapedesis.

EMBO J · 2026 · PMC13043941 · PMID 41813848

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highly significantno p-value reported

7B , direct comparison of endothelial junctions at sites of PMN transmigration with junctions of HUVEC without PMNs revealed a highly significant 10% drop in FRET efficiency, whereas no such effect was seen when plakoglobin expression was silenced.

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