New insights into the plasma and urinary metabolomic signatures of spontaneously hypertensive rats.

These analyses show significant or borderline significant enrichment of several pathways related to hypertension in plasma, namely steroid hormone biosynthesis (combined p value = 0.0049), primary bile acid biosynthesis (combined p value = 0.063), and arachidonic acid metabolism (combined p value = 0.084) for plasma and purine metabolism in urine (combined p value = 0.0071).

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