Hypobaric hypoxia can lead to an increase in lung dendritic cells and promote T-cell immunosuppression, thereby preventing the excessive progression of high-altitude pulmonary edema.

Front Immunol · 2026 · PMC13053275 · PMID 41953030

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an increasing trendno p-value reported

We found that there was no significant difference in the percentage of lungCD3 + T cells in the HH rats, while the absolute number showed an increasing trend ( Supplementary Figure 5A ).

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