Comparison of long-term prognoses between 3D-printed template-guided and conventional freehand interstitial brachytherapy for locally advanced cervical cancer: a single-center retrospective study.

Although PFS demonstrated a nonsignificant trend toward 3D-PTIB (70.8% vs. 62.3%; HR = 0.73, 95% CI: 0.53–1.00; p = 0.05), a substantial absolute improvement of 11.7% in local control was achieved with 3D-PTIB. 3.5 Multivariable analysis of survival outcomes Table 5 shows that multivariable Cox regression analyses, adjusted for age, FIGO stage, tumor diameter, parametrial invasion, lymph node status, and chemotherapy completion, demonstrated that 3D-PTIB remained an independent predictor of improved overall survival (aHR = 0.71, 95% CI: 0.52–0.97, p = 0.03).

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