Genetic determinants of BMI, diet, and fitness interact to partially explain anthropometric obesity traits but not the metabolic consequences of obesity in men and women.

Int J Obes (Lond) · 2026 · PMC13056523 · PMID 41720915

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highly significantp = 2.5 × 10 −8actually significant

While variance in BMI differed significantly between PRS groups (Levene’s test p = 0.015), the PRS effect remained highly significant when accounting for heterogeneity (Welch’s ANOVA F = 21.0, p = 2.5 × 10 −8 ).

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