In the case of elt-2 and daf-16 RNAi , we observed a trend towards decreased fmo-2 levels, which failed to reach significance because of the large magnitude of fmo-2 mRNA increase in clk-1 worms.
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Mild mitochondrial impairment activates overlapping longevity pathways converging on the flavin-containing monooxygenase FMO-2.
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