Virtual screening and cellular validation of dolutegravir as a BRD9 inhibitor for attenuating pyroptosis in peritoneal mesothelial cells.

Ren Fail · 2026 · PMC13059028 · PMID 41943612

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a decreasing trendno p-value reported

Western blot analysis showed that the expression levels of NLRP3, Caspase-1, and GSDMD-N were significantly higher in HG group, followed by a decreasing trend with the application of BRD9 inhibitors.

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