Additionally, RT-qPCR results demonstrated highly significant downregulation of the proliferation markers Ki67 and Pcna upon KLF4 overexpression and significant upregulation upon KLF4 knockdown, confirming that KLF4 has an inhibitory effect on the proliferation of SHF-DPCs (Fig. 2 i, j).
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Expression dynamics and functional roles of KLF4 during embryonic hair follicle development in cashmere goats.
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