Detection of circulating tumor DNA in colorectal cancer patients using a methylation-specific droplet digital PCR multiplex.

Mol Oncol · 2026 · PMC13060638 · PMID 41239188

Europe PMC DOI

hedged sentences

0.0450

closest p · 0.9× alpha

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boldest claim

The sentences

marginal significanceP = 0.045actually significant

A higher fraction of patients with a cT3–4 were ctDNA‐positive (74%) compared with cT1–2 (48%), with marginal significance ( P = 0.045).

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an increasing trendno p-value reported

While we observed an increasing trend in ctDNA positivity with advancing clinical stages, the differences were not statistically significant, likely due to the limited number of patients in each category.

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