Staged management of infected diabetic foot ulcers: a 300-patient cohort study on prognostic grading, pathogen dynamics, and individualized risk prediction.

Front Med (Lausanne) · 2026 · PMC13065669 · PMID 41970400

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highly significantno p-value reported

After adjusting for the time-varying effects of carbapenem use and revascularization, the hazard ratio for ulcer non-healing comparing Grade 4 to Grade 2 infections attenuated slightly from 4.76 to 4.21 but remained highly significant (95% CI: 2.95–6.01).

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