Molecular variants, clonal evolution and clinical relevance in pediatric and adult T-cell lymphoblastic neoplasia.

Blood Cancer J · 2026 · PMC13066408 · PMID 41927524

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highly significantno p-value reported

In pediatric T-LBL, highly significant trajectories included LOH_in_9p→NOTCH1 ( p adj = 0.0016), LOH_in_9p→NOTCH1→FBXW7 ( p adj = 0.0006) and LOH_in_9p→USP7→FBXW7 ( p adj = 0.0006).

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