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Prognostic application regarding PILE score and the pan-immune-inflammation value in diffuse large B-Cell Lymphoma.

BMC Immunol · 2026 · PMC13067569 · PMID 41782081

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highly significantno p-value reported
Although PIV did not demonstrate independent prognostic significance in median analysis, its prognostic association with OS and PFS in patients with DLBCL remained stable and highly significant as verified by analyses.Thus, PIV represents the pan-immune inflammatory index with the best prognostic performance in the present study.Meanwhile, PIV exhibited superior discriminative ability and clinical net benefit compared with other immune-inflammatory indices in ROC and DCA analyses.PIV remains a core indicator for evaluating the prognosis of DLBCL in this study.Additionally, the PILE score proved informative for predicting both PFS and OS, with individuals in the high-score group exhibiting markedly poorer outcomes.

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