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Comparison of the Effect of Co-Trimoxazole versus Co-Trimoxazole and Fluoroquinolones in Urinary Tract Infection Prophylaxis in Kidney Transplant Recipients: A Systematic Review and Meta-analysis.

J Res Pharm Pract · 2026 · PMC13067960 · PMID 41969591

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may be significantno p-value reported
This may be significant, as patients receiving broad-spectrum prophylaxis could be predisposed to infections with more resistant organisms in the future.[ 13 ] Another limitation is the low external validity; both studies were conducted in single centers (one in Iran and the other in the United States), and patterns of bacterial resistance and infection epidemiology differ across regions.

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