This trend can be better termed as an observed trend rather than a definitive escalation.
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The prevalence of diabetic retinopathy in type-2 diabetes in Pakistan: a systematic review and meta-analysis.
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The sentences
Although year of publication (β = 0.0092, p = 0.0573, R2 = 4.25) and working year (β = 0.0085, p = 0.0540, R2 = 4.45) showed positive trends, their effects were marginally nonsignificant.