IL3RA identified as novel biomarker and therapeutic target for ER<sup>+</sup> breast cancer through plasma proteome-wide mendelian randomization and TCGA database analysis.

Clin Proteomics · 2026 · PMC13072662 · PMID 41787256

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highly significantno p-value reported

In the ER + and ER + /PR + subgroup, immune cells such as neutrophils, M0 macrophages, and M2 macrophages were also found to exhibit highly significant correlations with IL3RA expression levels.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

IL3RA identified as novel biomarker and therapeutic target for ER&lt;sup&gt;+&lt;/sup&gt; breast cancer through plasma proteome-wide mendelian randomization and TCGA database analysis.

The sentences

IL3RA identified as novel biomarker and therapeutic target for ER<sup>+</sup> breast cancer through plasma proteome-wide mendelian randomization and TCGA database analysis.