Single-Cell and Spatial Transcriptomics Reveal That <i>TXNIP</i> and <i>BIRC3</i> Contribute to Human Prostate Tumor Progression.

In monocytes, highly significant enrichment was observed for regulation of inflammatory response (GO:0050727, p = 3.95 × 10 −21 ), positive regulation of innate immune response (GO:0045089, p = 2.69 × 10 −18 ), the innate immune response-activating signaling pathway (GO:0002758, p = 2.69 × 10 −16 ), canonical NF-kappaB signal transduction (GO:0007249, p = 3.00 × 10 −9 ), and the tumor necrosis factor-mediated signaling pathway (GO:0033209, p = 0.001).

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