The NLRP3 Inflammasome in Neuropsychiatric Disorders: Molecular Mechanisms and Emerging Therapeutic Strategies.

Int J Mol Sci · 2026 · PMC13073418 · PMID 41977314

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highly significantno p-value reported

This is highly significant because it suggests NLRP3 participates not only in inflammatory amplification, but in the pathological transition from amyloid accumulation to tau-mediated neurodegeneration.

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