Barely Significant
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Nuclear Lamins: A Molecular Bridge Coupling Extracellular Mechanical Cues to Intranuclear Signal Transduction and Gene Regulation.

Int J Mol Sci · 2026 · PMC13074085 · PMID 41977436

Europe PMCDOI
1
hedged sentence
0.0017
closest p · 0.0× alpha
0.0017
boldest claim

The sentences

highly significantp = 0.0017actually significant
have quantitatively analyzed the molecular interaction between SUN proteins and Lamin A using acceptor photobleaching FRET technology, showing that the FRET efficiency of SUN1 and Lamin A (about 14–16%) is significantly higher than that of SUN2 and Lamin A (about 8–10%), and the difference between the two was statistically highly significant ( p = 0.0017) [ 6 ].

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