Barely Significant
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Biological Activity of Hops (<i>Humulus lupulus</i> L.): Molecular Mechanisms and Significance for Human Health-A Review.

Nutrients · 2026 · PMC13075050 · PMID 41978108

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may be significantno p-value reported
Despite its low concentration in the starting material, its actual biological activity in the human body may be significant, owing to chemical and metabolic processes occurring both during hop processing and within the gastrointestinal tract and liver.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.