Cardiorespiratory cross-frequency coupling biomarker for sudden unexpected death in epilepsy.

Respiratory coupling above .25 Hz was highly significant ( p < .0001; Figure 3A ), whereas cardiac coupling above 1.7 Hz was modestly significant ( p < .0142; Figure 3B ). 3.1 Risk assessment model The individual seizure values underlying Figure S3 served as features for training a logistic model, producing propensity scores for each seizure, which further distinguished SUDEP from non‐SUDEP cases.

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