Managing dry eye disease - a review of selected traditional Chinese medicine and some of their metabolites focusing on molecular mechanisms and signaling pathways.

Treatment with Modified Siwei Dafa Powder (5.89 g/kg/d, oral) for 7 days improved clinical signs (tear secretion, BUT, corneal repair) and modulated apoptosis in lacrimal gland tissue by significantly downregulating Bax and Caspase-9 (with Caspase-3 showing a decreasing trend), upregulating Bcl-2, and reducing IL-6 ( Chen L. et al., 2023 ). 6.8 Huashi Runjing Decoction Clinical studies have demonstrated that the Huashi Runjing Decoction possesses multiple therapeutic properties, including dampness removal, liver nourishment, yin boosting, collaterals unblocking, ocular moisturization, and vision improvement.

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