Co-produced evidence-based recommendations for cascade screening and secondary prevention in the relatives of people diagnosed with non-syndromic thoracic aortic disease.

3.5.4 Implementation considerations Costs deriving from the implementation of an unselected combined approach to screening in TAD might be significant, but no direct evidence is available for a cost-effectiveness analysis. 3.6 Pre-test genetic counselling vs. standard care in families of people with acute aortic syndromes? 3.6.1 Recommendation We could not make a recommendation for this question.

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