highly significantp < 0.01
Statistical differences between groups were considered significant at p < 0.05, highly significant at p < 0.01, and extremely significant at p < 0.001.
Statistical differences between groups were considered significant at p < 0.05, highly significant at p < 0.01, and extremely significant at p < 0.001.
During the treatment period, the body weight of mice in each group showed a decreasing trend over time (Fig. 3 d).