Barely Significant
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Global, regional, and national burden of chronic respiratory diseases among perimenopausal women, 1990-2021: an analysis for the Global Burden of Disease Study 2021.

J Thorac Dis · 2026 · PMC13077387 · PMID 41988290

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an increasing trendno p-value reported
An increasing trend in the ASIR and ASPR was observed in five regions of COPD: Caribbean, Central Sub-Saharan Africa, high-income North America, North Africa and Middle East and Western Sub-Saharan Africa.

also in 63,971 other papers

a decreasing trendno p-value reported
The ASPRs of the four CRDs showed a decreasing trend and were most significant for asthma (AAPC =−2.06, 95% CI: −2.08 to −2.03) ( Table 1 ).

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.