Year of publication was negatively associated with the distribution of acquired thrombophilia (slope = −0.046, p = 0.0001) and anatomical factors (slope = −0.031, p = 0.02), indicating a decreasing trend in reported proportions of these etiological categories over time ( Supplementary Table S13 ; Supplementary Figures S29 – S35 ).
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Recurrent pregnancy loss: systematic review and meta-analysis of overall prevalence and the distribution of major etiological categories.
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