of borderline significancep < 0.05
For studies with a reported mean tumor diameter <2 cm and ≥2 cm, the pooled sensitivity and specificity were 0.65 and 0.77 with an AUC of 0.77, and 0.78 and 0.73 with an AUC of 0.82, respectively; no significant between-group difference was observed in sensitivity ( p = 0.22), whereas the difference in AUC was of borderline significance ( p < 0.05).