3 D) and an increasing trend in LVPWd ( Fig. 3 F).
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Osthole attenuates trastuzumab-induced cardiotoxicity in mice by enhancing autophagy via regulating the p38MAPK/mTOR signaling pathway.
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The changes in LVIDd and LVPWd after OST pretreatment did not differ significantly from those in the TRZ group, although there was a decreasing trend in LVIDd ( Fig. 3 D) and an increasing trend in LVPWd ( Fig. 3 F).