Barely Significant
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De-2-hydroxyisobutyrylation of clusterin modulates neuropathology and memory deficits in an Alzheimer's disease mouse model.

Cell Commun Signal · 2026 · PMC13085400 · PMID 41803852

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a pronounced trendno p-value reported
These findings indicated that there is a pronounced trend toward Khib upregulation in the AD brain.

also in 237 other papers

highly significantno p-value reported
This intervention suppressed the progression of amyloid pathology over a critical two-month period in the APP/PS1 model, demonstrating a highly significant disease-modifying effect.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.