Single-cell RNA-seq and in vitro study reveal Fusobacterium nucleatum impairs β-cell identity in type 2 diabetes via the NF-κB-CDKN1C axis.

J Transl Med · 2026 · PMC13085606 · PMID 41803883

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an increasing trendno p-value reported

The analysis similarly revealed an increasing trend in the loss of β-cell identity within the T2D group (Fig.

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a decreasing trendno p-value reported

The α-cells showed a gradually increasing trend, while the δ- and PP cells showed a decreasing trend (Fig.

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