Efficacy of scalp cooling system versus chemical cooling cap in preventing chemotherapy-induced alopecia in breast cancer (COHAIR Study): a prospective randomized trial.

Notably, the incidence of adverse effects in the scalp cooling system group showed a decreasing trend during treatment, while the chemical cooling cap group maintained relatively stable rates throughout the treatment course ( Fig. 3 ). 3.4 Psychological distress Baseline assessments revealed no statistically significant difference in anxiety or depression scores between the two treatment groups.

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