Preparation and Antitumor Activity of METTL3 SiRNA Nanoparticles Carried by Hypoxia Sensitive Polymer (mPEG-Azo-PEI).

Int J Nanomedicine · 2026 · PMC13091633 · PMID 42005705

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an increasing trendno p-value reported

Discussion Worldwide morbidity and mortality data on cancer of colon-rectum depict an increasing trend, and it is considered the third most widespread carcinoma. 35 Chemotherapy is greatly affected by chemoresistance, which is a common malignancy of the gastro-intestinal tract, chemotherapy of the disease is greatly affected by chemoresistance. 36 The ability of cancer cells of the colon and rectum

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