Perioperative psycho-behavioral stress promotes cancer metastasis beyond the impact of surgery: Neuroendocrine and tumor molecular mediating mechanisms.

Brain Behav Immun Health · 2026 · PMC13091779 · PMID 42011257

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

marginally significantno p-value reported

The drug treatment in the stress group downregulated HIF activity, with a marginally significant decrease in HIF-1a and a significant decrease in HIF-2a, another member of the HIF TF family.

also in 26,082 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.