Alcohol use disorder increases risk of major adverse limb events following lower-extremity revascularization for chronic limb-threatening ischemia.

J Vasc Surg · 2026 · PMC13092323 · PMID 41748039

Europe PMC DOI

hedged sentence

0.2950

closest p · 5.9× alpha

0.2950

boldest claim

The sentences

failed to reach significanceP = .295not close (p > 0.1)

Although major revascularization failed to reach significance (sHR, 1.14; 95% CI, 0.89-1.47; P = .295), AUD conferred higher 1-year risk of major amputation (sHR, 1.94; 95% CI, 1.65-2.36; P < .001) and mortality (aHR, 1.51; 95% CI, 1.09-2.09; P = .013).

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